Remote digital multi‐day learning curves detect subtle cognitive differences associated with plasma <i>p</i> ‐tau217 among cognitively unimpaired older adults

These results complement our previous work that multi-day BRANCH may improve the detection of very subtle memory deficits that are associated with early AD pathophysiology. Combining a remote and sensitive cognitive paradigm like BRANCH with plasma biomarkers may facilitate scalable detection of those at risk for AD-related cognitive decline.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_106782
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Remote digital multi‐day learning curves detect subtle cognitive differences associated with plasma p ‐tau217 among cognitively unimpaired older adults

Mark A. Dubbelman, Roos J. Jutten, Daniel Soberanes, Gad Marshall et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Remote digital multi‐day learning curves detect subtle cognitive differences associated with plasma p ‐tau217 among cognitively unimpaired older adults

Mark A. Dubbelman, Roos J. Jutten, Daniel Soberanes, Gad Marshall, K. N. Johnson, Rebecca England Amariglio, Lia D'Aquila, Hyun‐Sik Yang, Deborah Blacker, Hairin Kim, Dorene M. Rentz, Reisa A. Sperling, Kathryn V Papp
article en

Abstract

These results complement our previous work that multi-day BRANCH may improve the detection of very subtle memory deficits that are associated with early AD pathophysiology. Combining a remote and sensitive cognitive paradigm like BRANCH with plasma biomarkers may facilitate scalable detection of those at risk for AD-related cognitive decline.

Alzheimer s & DementiaVol. 21(S3)
Brigham and Women's Hospital (US), Harvard University (US), Massachusetts General Hospital (US)
Quality Education
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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