CD31 <sup>+</sup> small extracellular vesicles as a novel biomarker for vascular injury and cognitive impairment
Our results highlight that the percentage of CD31<sup>+</sup> EVs is significantly correlated with vascular brain injury, and the combination of CD31<sup>+</sup> EVs with p-tau181 shows excellent discriminative performance. This also provides an opportunity for us to identify cerebrovascular EVs from plasma, enabling early detection of changes in the vasculature.
Authors
- Tongyao You (ORCID: https://orcid.org/0000-0002-6345-6457)
- Mei Nu Cui
- Qiang Dong
- Yingzhe Wang
- Qi Han
Institutions
- Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101397
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00