Impact of genetic counseling and testing in individuals at high risk for Alzheimer ´s Disease from Latin America
Our primary finding is showed no clinically meaningful differences in distress-related outcomes between individuals learning their genetic status relative to those who didn't. Our findings confirm that genetic testing is well-tolerated when using a protocol that provides screening, education, counseling, and follow-up sessions. In addition, we provide preliminary insights into the psychological impact associated with learning one's genetic status in familial AD, contributing significantly to the field of medical genetics in the region.
Authors
- Pablo Bagnati (ORCID: https://orcid.org/0000-0003-2801-0537)
- Mauricio Arcos Burgos
- Laura Ramirez Aguilar
- Ezequiel Surace (ORCID: https://orcid.org/0000-0001-8492-9578)
- David Fernando Aguillon (ORCID: https://orcid.org/0000-0003-2283-536X)
- Juan D Barbaran Manco
- Carlos M Restrepo‐Fernández
- Beatriz E Mora‐Henao
- Ellen Ziegemeier
- Patricio Chrem
- Gabriel Vargas (ORCID: https://orcid.org/0000-0001-8511-6042)
- Ricardo Allegri (ORCID: https://orcid.org/0000-0001-7166-1234)
- Eric McDade (ORCID: https://orcid.org/0000-0002-6764-3866)
- Claudia Madrigal
- María Lecuona (ORCID: https://orcid.org/0000-0002-7388-4842)
- Cláudia Ramos (ORCID: https://orcid.org/0000-0002-0030-4501)
- Jorge J. Llibre‐Guerra (ORCID: https://orcid.org/0000-0002-2137-7750)
- M. Castaño
- Gabriela Vigo
- Juan Pablo Picasso
- Erika Mariana Longoria
- Yudy M Leon‐Varela
- Francisco Lopera
- Randall J. Bateman
- Luz E Varela Londoño
Institutions
- National University of Salta (AR)
- Washington University in St. Louis (US)
- Universidad de Antioquia (CO)
- Tecnológico Nacional de México (MX)
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (AR)
- Universidad de Medellín (CO)
- Instituto de Investigación de Enfermedades Raras (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_099318
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00