Plasma‐based Brain Age as a Biomarker for Cognitive Health and Risk of Brain‐Related Diseases

Our findings suggest that brain aging is associated with cognitive performance and increased risk of brain-related disease in two longitudinal cohorts utilizing different proteomics platforms. Our findings highlight the potential of identifying novel plasma-based biomarkers for monitoring cognitive health and identifying individuals at risk of developing brain-related diseases.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103849
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Plasma‐based Brain Age as a Biomarker for Cognitive Health and Risk of Brain‐Related Diseases

Biqi Wang, Honghuang Lin, Joanne M. Murabito, Huitong Ding et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Plasma‐based Brain Age as a Biomarker for Cognitive Health and Risk of Brain‐Related Diseases

Biqi Wang, Honghuang Lin, Joanne M. Murabito, Huitong Ding, Mayra S. Tisminetzky, Derek Qi
article en

Abstract

Our findings suggest that brain aging is associated with cognitive performance and increased risk of brain-related disease in two longitudinal cohorts utilizing different proteomics platforms. Our findings highlight the potential of identifying novel plasma-based biomarkers for monitoring cognitive health and identifying individuals at risk of developing brain-related diseases.

Alzheimer s & DementiaVol. 21(S2)
Boston University (US), University of Massachusetts Chan Medical School (US)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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