A Multiscale Ex Vivo Method to Investigate Intervertebral Disc Strain and Fiber Recruitment in Anterolateral Bending Using 9. <scp>4T MRI</scp> ‐ <scp>DVC</scp> and <scp>DIC</scp> Microscopy
This study confirms the suitability of MRI-DVC combined with DIC microscopy for relating macroscopic strains to microscopic fiber crimp, and for identifying regions of high strain across multiple length scales. Under AL-bending, this methodology revealed that the disc's posterior region exhibited taut fibers, which may contribute to its susceptibility to herniation.
Authors
- Ashvin Thambyah (ORCID: https://orcid.org/0000-0003-2766-0263)
- N. Newell
- K. A. Raftery
- V. M. van Heeswijk
- T. D. Slater
Institutions
- University of Auckland (NZ)
- Imperial College London (GB)
Publication Details
- Journal
- JOR Spine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jsp2.70154
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Royal Society
- Engineering and Physical Sciences Research Council