Analytical Study of Some Drug Brands Used to Treat Stomach Acidity

This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC).

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Publication Details

Journal
International Journal of Pharmacy and Chemistry
Published
2025-12-24
DOI
https://doi.org/10.11648/j.ijpc.20251106.12
Primary Topic
Pharmacy and Medical Practices
Type
article
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article

Analytical Study of Some Drug Brands Used to Treat Stomach Acidity

Ruwaida Al-Rabshi, Najat Naji, Aisha Benjuma, Rabia Eshkourfu
International Journal of Pharmacy and Chemistry
Pharmacy and Medical Practices
article

Analytical Study of Some Drug Brands Used to Treat Stomach Acidity

Ruwaida Al-Rabshi, Najat Naji, Aisha Benjuma, Rabia Eshkourfu
article en

Abstract

This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC).

International Journal of Pharmacy and ChemistryVol. 11(6)
University Elmergib (LY)
Openalex Percentile: Top 30%
Pharmacy and Medical Practices
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