Correlation of prefrontal‐based resting state functional connectivity with the degree of cognitive impairment in Alzheimer's disease: a functional near‐infrared spectroscopy study
Different resting-state prefrontal FC strength were observed at different cognitive levels, and FC strength in the left dorsolateral PFC, where BA46.L and BA9.L are located, emerged as a key region for cortical dysfunction in cognitive impairment. Significant variations in prefrontal FC strength were identified across different time windows of the resting state, particularly highlighting the importance of BA45.R in distinguishing MCI from NC.
Authors
- Ming Chen (ORCID: https://orcid.org/0000-0001-9869-4036)
- Wei Zhang (ORCID: https://orcid.org/0000-0001-7800-3189)
- Weihua Yu
- Yang Lü
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101537
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00