Lymphocytic Esophagitis Mimicking Allergic Esophagitis: A Case Report

Lymphocytic esophagitis (LE) is a rare inflammatory condition of the esophagus, characterized by intraepithelial lymphocytic infiltration of the esophageal mucosa. Despite its increasing recognition recently, standardized guidelines for diagnosis and management are still lacking. LE is frequently associated with conditions that alter esophageal pH, including gastroesophageal reflux disease (GERD), Crohn's disease, and diabetes mellitus. This report describes a 55-year-old male who presented with dysphagia and intermittent heartburn. Esophagogastroduodenoscopy (EGD) revealed LE along with incidental <i>Helicobacter pylori </i>gastritis. Management typically focuses on addressing underlying conditions, with proton pump inhibitors (PPIs) and topical steroids being the most common therapeutic approaches. The discussion highlights the prevalence, diagnostic challenges, and treatment strategies for LE.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-12-24
DOI
https://doi.org/10.7759/cureus.100033
Primary Topic
Eosinophilic Esophagitis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Lymphocytic Esophagitis Mimicking Allergic Esophagitis: A Case Report

Jasbir Makker, Hassan A Muntazir, Rahul Reddy Nallapareddy
Cureus
Eosinophilic Esophagitis
article

Lymphocytic Esophagitis Mimicking Allergic Esophagitis: A Case Report

Jasbir Makker, Hassan A Muntazir, Rahul Reddy Nallapareddy
article en

Abstract

Lymphocytic esophagitis (LE) is a rare inflammatory condition of the esophagus, characterized by intraepithelial lymphocytic infiltration of the esophageal mucosa. Despite its increasing recognition recently, standardized guidelines for diagnosis and management are still lacking. LE is frequently associated with conditions that alter esophageal pH, including gastroesophageal reflux disease (GERD), Crohn's disease, and diabetes mellitus. This report describes a 55-year-old male who presented with dysphagia and intermittent heartburn. Esophagogastroduodenoscopy (EGD) revealed LE along with incidental <i>Helicobacter pylori </i>gastritis. Management typically focuses on addressing underlying conditions, with proton pump inhibitors (PPIs) and topical steroids being the most common therapeutic approaches. The discussion highlights the prevalence, diagnostic challenges, and treatment strategies for LE.

CureusVol. 17(12)
Boston University (US), Montefiore Health System (US), MemorialCare Health System (US)
Good health and well-being
Openalex Percentile: Top 26%
Eosinophilic Esophagitis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Lymphocytic Esophagitis Mimicking Allergic Esophagitis: A Case Report — Jasbir Makker, Hassan A Muntazir, et al. · Cureus (2025) | TGRS Research Map | TGRS