Small non‐coding RNA transcriptomic profiling of neural cell‐types in Alzheimer's disease model mice
We observed unique sncRNA signatures in astrocytes, microglia and neurons that were correlated with gene transcriptional changes and association with amyloid pathology. This study is a valuable resource for exploring the role of sncRNA in different neural cell types, unique sncRNA signatures associated with AD like pathologies and their potential use as biomarkers in AD.
Authors
- Nicholas F. Fitz (ORCID: https://orcid.org/0000-0001-6938-6536)
- Radosveta Koldamova (ORCID: https://orcid.org/0000-0002-6761-0984)
- Iliya Lefterov (ORCID: https://orcid.org/0000-0002-0249-0280)
- MD Shahnu Alam
Institutions
- University of Pittsburgh (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106595
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00