Markers of Blood‐Brain Barrier Permeability and Immune Exhaustion are Present in Patients with Post‐COVID‐19 Brain Fog Compared to Controls
Lower cytokine levels, increased markers of BBB disruption, and altered markers of tau pathology were observed in patients with brain fog and COV+ subjects with MCI, which may suggest immune exhaustion, increased BBB permeability, and disrupted tau processing as possible mechanisms of post-COVID-19 brain fog.
Authors
- Amin Yakubov (ORCID: https://orcid.org/0000-0002-2499-2126)
- Arjun V. Masurkar (ORCID: https://orcid.org/0000-0002-2498-2059)
- Sujata Thawani
- Rebecca A. Betensky (ORCID: https://orcid.org/0000-0002-3793-1437)
- Mukundan Attur (ORCID: https://orcid.org/0000-0001-7080-8118)
- Alok Vedvyas
- Daria Sergeevna Vasilchenko
- Karyn Marsh (ORCID: https://orcid.org/0009-0003-9057-1551)
- Ludovic Debure
- Joshua Chodosh (ORCID: https://orcid.org/0000-0001-7784-4306)
- Wajiha Ahmed (ORCID: https://orcid.org/0009-0007-8121-0307)
- Mobeena Ghuman
- Jon Links
- Salma Hammam
- Yulin Ge
- Jennifer A. Frontera
- Allal Boutajangout
- Li Jiang
- Thomas Wisniewski
- Manisha Bohara
Institutions
- Pace University (US)
- NYU Langone Health (US)
- Cognitive Research (United States) (US)
- New York University Langone Orthopedic Hospital (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103583
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00