Identification of Differentially Abundant Proteins in Alzheimer's, Synuclein, and Vascular Pathologies Using the NULISA proteomics platform
The NULISA platform identified distinct DAPs for AD, synuclein, and vascular pathology. These had minimal overlap and significant dynamic changes along the disease progression and load which highlights the potential of proteomics panels for differentiating co-pathologies in neurodegenerative diseases.
Authors
- Inès Hristovska (ORCID: https://orcid.org/0000-0003-4779-4103)
- Anna Orduña Dolado (ORCID: https://orcid.org/0009-0003-8287-0754)
- Gemma Salvadó (ORCID: https://orcid.org/0000-0002-5210-9230)
- Oskar H. Hansson
- Kübra Tan (ORCID: https://orcid.org/0000-0002-9092-2118)
- Wiebke Traichel
- Alexa Pichet Binette
- Andrea Benedet
- Niklas Mattsson‐Carlgren
- Sebastian Palmqvist
- Ilaria Pola
- Shorena Janelidze
- Nicholas Ashton
Institutions
- King's College London (GB)
- Lund University (SE)
- Stavanger University Hospital (NO)
- Centre for Mental Health (GB)
- Profu (Sweden) (SE)
- Pasqual Maragall Foundation (ES)
- Barcelonaβeta Brain Research Center (ES)
- Skåne University Hospital (SE)
- Banner Alzheimer’s Institute
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099280
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00