Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities
These findings highlight NfL as a biomarker reflecting neurodegenerative and vascular aspects of brain aging, with vascular pathology driving neurodegeneration.
Authors
- Konstantinos Arfanakis (ORCID: https://orcid.org/0000-0001-9705-597X)
- Arnold M Evia (ORCID: https://orcid.org/0000-0003-2262-890X)
- Khalid Saifullah
- Gulam Mahfuz Chowdhury
- David A. A. Bennett
- Julie A Schneider
Institutions
- Rush University Medical Center (US)
- Illinois Institute of Technology (US)
- Rush University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101837
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00