Portable Low‐Field MRI for Rapid Detection and Monitoring of ARIA in Lecanemab‐Treated Alzheimer's Disease Patients: A Pilot Study
This pilot study suggests that portable LF MRI can detect and monitor ARIA-E in patients treated with lecanemab, potentially circumventing delays associated with HF MRI. Although image quality is lower than HF MRI, the ability to guide therapeutic decisions promptly may prove clinically significant. Further larger-scale studies are warranted to validate these initial findings, refine imaging protocols, and explore the broader role of LF MRI in routine ARIA screening and follow-up.
Authors
- Shenghua Zhu
- Jarrel Seah (ORCID: https://orcid.org/0000-0002-2305-7873)
- Saurabh Rohatgi (ORCID: https://orcid.org/0000-0002-4000-7878)
- Javier Romero (ORCID: https://orcid.org/0000-0001-5546-9939)
- John C. Ford (ORCID: https://orcid.org/0000-0001-6133-5224)
- Esteban Calle Cadavid
Institutions
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_100090
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00