Lecanemab in the treatment of early Alzheimer's disease: An observational study based on 7.0T ultra‐high field MRI

1. Lecanemab treatment in AD patients from Hunan, China, is generally safe, though its long-term efficacy requires further investigation. 2. The use of 7.0T MRI, particularly its SWI sequence, enhances monitoring of microbleeds and improves safety surveillance. Furthermore, DTI-ALPS, which reflects the glymphatic function, presents as a potential imaging marker for assessing treatment efficacy.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_100048
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Lecanemab in the treatment of early Alzheimer's disease: An observational study based on 7.0T ultra‐high field MRI

Haokun Liu, Bin Jiao, Lu Shen, Keying Fang et al.
Alzheimer s & Dementia
Cerebrospinal fluid and hydrocephalus
article

Lecanemab in the treatment of early Alzheimer's disease: An observational study based on 7.0T ultra‐high field MRI

Haokun Liu, Bin Jiao, Lu Shen, Keying Fang, Weiwei Zhang
article en

Abstract

1. Lecanemab treatment in AD patients from Hunan, China, is generally safe, though its long-term efficacy requires further investigation. 2. The use of 7.0T MRI, particularly its SWI sequence, enhances monitoring of microbleeds and improves safety surveillance. Furthermore, DTI-ALPS, which reflects the glymphatic function, presents as a potential imaging marker for assessing treatment efficacy.

Alzheimer s & DementiaVol. 21(S2)
Central South University (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 37%
Cerebrospinal fluid and hydrocephalus
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