Brain‐Peripheral Proteome Crosstalk in Alzheimer's Disease with and without Diabetes Mellitus

Overall, muscle peptides were mostly related to pathological AD, while serum peptides were more likely to be related to IR in AD. The crosstalk between central and peripheral peptide expression may be the first step in uncovering AD markers in distant tissues.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_102725
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Brain‐Peripheral Proteome Crosstalk in Alzheimer's Disease with and without Diabetes Mellitus

Shinya Tasaki, Vishal Sarsani, Ana W. Capuano, ANAT YASKOLKA MEIR et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Brain‐Peripheral Proteome Crosstalk in Alzheimer's Disease with and without Diabetes Mellitus

Shinya Tasaki, Vishal Sarsani, Ana W. Capuano, ANAT YASKOLKA MEIR, Vladislav Petyuk, Z.O.E. Arvanitakis, Xingyan Wang, Liming Liang, David A. A. Bennett
article en

Abstract

Overall, muscle peptides were mostly related to pathological AD, while serum peptides were more likely to be related to IR in AD. The crosstalk between central and peripheral peptide expression may be the first step in uncovering AD markers in distant tissues.

Alzheimer s & DementiaVol. 21(S3)
Broad Institute (US), Rush University Medical Center (US), Harvard University (US), Pacific Northwest National Laboratory (US)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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Brain‐Peripheral Proteome Crosstalk in Alzheimer's Disease with and without Diabetes Mellitus — Shinya Tasaki, Vishal Sarsani, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS