Sex differences in associations between melatonin secretion, core body temperature, and cognitive function in older adults
Melatonin release is strongly coupled to nocturnal Tdrop, however the timing and strength of this coupling exhibit sex differences. Greater melatonin and Tdrop may be protective for cognition particularly among female older adults. Future research in younger adults should determine whether aging-related changes (e.g., menopause) influence observed sex differences.
Authors
- Robert T. Krafty (ORCID: https://orcid.org/0000-0003-1478-6430)
- A. K. Govil
- Meryl A Butters
- H. Matthew Lehrer
- Daniel J Buysse
- Hau‐Tieng Wu
- Esther M Blessing
Institutions
- Emory University (US)
- University of Pittsburgh (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_107057
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.00