Reports of elevated cognitive decline in autistic adults are linked to high anticholinergic potency
Ratings from dementia screeners dovetail with healthcare claims data by revealing relatively common reports of cognitive decline in autistic adults. Furthermore, among autistic adults, anticholinergic medication use is high, and increased anticholinergic potency is linked to reports of cognitive decline, often at younger ages than in the general population.
Authors
- Nancy Lee (ORCID: https://orcid.org/0000-0002-6663-0713)
- Claire B. Klein (ORCID: https://orcid.org/0000-0002-3480-2066)
- Laura G. Klinger (ORCID: https://orcid.org/0000-0002-3399-9039)
- Gregory L. Wallace (ORCID: https://orcid.org/0000-0003-0329-5054)
- Goldie A. McQuaid (ORCID: https://orcid.org/0000-0003-3614-616X)
- Rebecca A. Charlton (ORCID: https://orcid.org/0000-0002-3326-8762)
- Neha Ahmed
- Sean C Duane
- Annissa DeSilva
Institutions
- University of North Carolina at Chapel Hill (US)
- George Mason University (US)
- George Washington University (US)
- Goldsmiths University of London (GB)
- Drexel University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_100513
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00