Lecanemab treatment for Alzheimer's Disease of varying severities and associated serum biomarkers monitoring: a real‐world study

In the real world, lecanemab may be safe and effective in the treatment of mild-to-moderate AD, and dynamic monitoring of serum p-tau 181 may be helpful to observe the efficacy during treatment. AD patients with severe cognitive impairment and significant white matter lesions should be closely monitored for adverse reactions, such as ARIA.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101739
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Lecanemab treatment for Alzheimer's Disease of varying severities and associated serum biomarkers monitoring: a real‐world study

Xueping Chen
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Lecanemab treatment for Alzheimer's Disease of varying severities and associated serum biomarkers monitoring: a real‐world study

Xueping Chen
article en

Abstract

In the real world, lecanemab may be safe and effective in the treatment of mild-to-moderate AD, and dynamic monitoring of serum p-tau 181 may be helpful to observe the efficacy during treatment. AD patients with severe cognitive impairment and significant white matter lesions should be closely monitored for adverse reactions, such as ARIA.

Alzheimer s & DementiaVol. 21(S2)
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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Lecanemab treatment for Alzheimer's Disease of varying severities and associated serum biomarkers monitoring: a real‐world study — Xueping Chen · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS