EFFICACY OF GRANTHOKTA SODHANA (VAMANA–VIRECHANA–YOGABASTI–UTTARA BASTI) IN FEMALE INFERTILITY: AN OBSERVATIONAL CLINICAL STUDY ON 10 PATIENTS

Background: Female infertility is a growing concern globally, often attributed to hormonal imbalances, anovulation, polycystic ovarian disease (PCOD), thin endometrium, and uterine factors. In Ayurveda, Granthokta Śodhana represents a classical detoxification protocol designed to rectify imbalances in Dosha, Dhatu, Agni, and Artavavaha Srotas. Objective: This study aimed to assess the efficacy of a sequential Granthokta Panchakarma regimen—comprising Vamana, Virechana, Yogabasti, and Uttara Basti—in improving fertility outcomes among women with primary and secondary infertility. Methods: A prospective observational clinical study was conducted involving 10 female patients diagnosed with infertility. Participants underwent classical preparatory procedures (Snehapāna and Svedana), followed by Vamana, Virechana, an 8-day Yogabasti course, and three cycles of Uttara Basti. Key outcomes included menstrual regularity, folliculometry, endometrial thickness, ovulation status, symptomatic relief, and conception rates. Results: Significant improvements were observed in over 80% of patients. Ovulation was restored in 80% of cases, menstrual regularity improved in 90%, endometrial thickness enhanced in 70%, and 50% (5/10) achieved conception within 3 months post-therapy. Conclusion The classical Granthokta Śodhana sequence demonstrates promising efficacy as a non-invasive Ayurvedic intervention for female infertility, enhancing reproductive parameters and conception rates.