Association of cardiovascular disease risk and blood biomarkers of Alzheimer's disease
Findings suggest that higher predicted CVD risk was associated with higher expression of neurodegenerative biomarker NFL, independent of age and sex. This finding may indicate that CVDrisk factors may play a critical role in neurodegenerative pathways. Future studies that examine longitudinal associations and synergistic interactions between CVD risk factors and AD biomarkers are needed.
Authors
- Grace Austin (ORCID: https://orcid.org/0000-0002-3936-6793)
- Manohar L. Garg (ORCID: https://orcid.org/0000-0003-0514-0865)
- Shaun Eslick
- Ralph N Martins
- Jessica Ferguson
Institutions
- University of Newcastle Australia (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100656
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00