Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; mediators of vascular contributions to cognitive impairment
These findings suggest that among individuals with T2DM and depression, elevated peripheral blood apoptosis markers are associated with cerebral microvascular complications, pointing to unique pathophysiological elements underlying mood and metabolic comorbidity.
Authors
- Bradley J. MacIntosh (ORCID: https://orcid.org/0000-0001-7300-2355)
- Yong‐Chuan Wong
- Si Won Ryoo
- Myuri Ruthirakuhan
- Sofia Perfetto
- Celine H.L. Huang
- Walter Swardfager
Institutions
- University of Toronto (CA)
- Sunnybrook Hospital (CA)
- Sunnybrook Research Institute
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100566
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00