Cerebrospinal Fluid Biomarkers Profiling in Older Brazilians reveals that CSF leptin is associated with obesity but not with cognitive decline
Obesity was primarily related to changes in CSF leptin and negatively associated with CD. However, the effects of obesity in CD decline are not associated with CSF analytes evaluated.
Authors
- Felipe C. Ribeiro (ORCID: https://orcid.org/0000-0003-3028-3307)
- Fabrício A. Pamplona (ORCID: https://orcid.org/0000-0002-0376-1644)
- Bart Vanderborght (ORCID: https://orcid.org/0000-0003-3964-6928)
- Mychael V. Lourenco (ORCID: https://orcid.org/0000-0002-1078-0296)
- Felipe Kenji Sudo (ORCID: https://orcid.org/0000-0003-4738-1368)
- Sérgio T. Ferreira (ORCID: https://orcid.org/0000-0001-7160-9866)
- Guilherme B. de Freitas (ORCID: https://orcid.org/0000-0003-4614-4280)
- Fernanda Guarino De Felice
- Douglas P. Munoz
- Fernanda G. Q. Barros‐Aragão
- Fernanda Tovar‐Moll
- Luis E. Santos
- Paulo E. Mattos
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Queen's University (CA)
- D’Or Institute for Research and Education (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101317
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00