Joint Association of Genetic Risk and Perceived Neighborhood Disorder with Dementia Across Diverse Populations: Results from All of Us
APOE and PND were jointly associated with dementia risk. Future research should include additional social measures, more genes, ADRD subtypes, and larger sample sizes to understand gene-environment interaction in dementia.
Authors
- Peter T. Nelson (ORCID: https://orcid.org/0000-0002-6161-1265)
- Yuriko Katsumata (ORCID: https://orcid.org/0000-0002-0188-8094)
- Erin L. Abner (ORCID: https://orcid.org/0000-0002-9566-4111)
- Yucong Sang
- Inori Tsuchiya
- Khine Zin Aung (ORCID: https://orcid.org/0009-0000-3793-6927)
- David W. Fardo (ORCID: https://orcid.org/0000-0002-7207-4696)
- Bryan D James
- Xian Wu
- Jing Zhang
- Jordan Brown
Institutions
- Rush University Medical Center (US)
- University of Kentucky (US)
- Rush University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107428
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00