Unveiling the overlooked: Multiallelic Variants in Brain Arteriolosclerosis
We investigated possible associations between human multiallelic variants and B-ASC risk. These are underexplored areas - both the genetic phenomena of multiallelic variants, and B-ASC as a dementia-driving pathology. Identifying novel genetic variants putatively contributing to the pathogenesis of B-ASC will move the field forward although validation with independent datasets is required.
Authors
- Peter T. Nelson (ORCID: https://orcid.org/0000-0002-6161-1265)
- Yuriko Katsumata (ORCID: https://orcid.org/0000-0002-0188-8094)
- Lincoln M. P. Shade (ORCID: https://orcid.org/0000-0001-6093-4823)
- Erin L. Abner (ORCID: https://orcid.org/0000-0002-9566-4111)
- Inori Tsuchiya
- Khine Zin Aung (ORCID: https://orcid.org/0009-0000-3793-6927)
- David W. Fardo (ORCID: https://orcid.org/0000-0002-7207-4696)
- Xian Wu
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106206
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00