Enhancing the Antidepressant Efficacy of Quercetin via Brain-Targeted Lipid Nanocarriers: Fabrication, Characterization, and Evaluation
The lipid nanodrug delivery system QNP exhibit sustained drug release and enhanced cellular uptake. By virtue of safety and improved delivery efficiency, they multidimensionally augment the therapeutic efficacy of antidepressants. This is crucial for translating quercetin from a dietary supplement into a precision antidepressant.
Authors
- Mingtang Zeng
- Linjin Xiong
- Wen Li (ORCID: https://orcid.org/0000-0002-4936-8143)
- Tao Chen (ORCID: https://orcid.org/0000-0001-5141-7170)
- Chenglong Wang (ORCID: https://orcid.org/0000-0002-3567-5759)
- Zhichan Cheng
Institutions
- Sichuan University (CN)
- Southwest Medical University (CN)
- West China Hospital of Sichuan University (CN)
- Maternal and Child Health Hospital of Sichuan Province (CN)
- Chongqing Emergency Medical Center (CN)
- Second People’s Hospital of Yibin (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijn.s556128
- Citations
- 1
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.79