Synergistic Neuroprotective Effects of a Plant‐Derived Alkaloid and Insulin‐like Growth Factor‐1 on SH‐SY5Y Cells: Targeting the Wnt/β‐Catenin Pathway in Alzheimer's Disease
This study highlights the significant neuroprotective potential of combining a natural alkaloid and IGF-1 against Aβ-induced toxicity, presenting a novel and promising therapeutic strategy for AD. Future research should aim to elucidate the detailed mechanisms underlying these protective effects and confirm their efficacy in in vivo models.
Authors
- Prajjwal Sharma
Institutions
- Central University of Punjab (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_096869
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00