Epigenetic Approaches to Diagnosis and Therapy of COVID-19: Features of Differential DNA Methylation Profile as Potential Targets for Therapy by the Method of RNA Interference

In this article the role of epigenetic factors, in particular, DNA methylation, in the processes of interaction of the SARS-CoV-2 virus with the human body and in the pathogenesis of COVID-19 is considered. An overview of experimental studies on the use of microRNA to regulate the expression of genes processed during the interaction of the virus with the host body is presented. A potential new strategy in the diagnosis and therapy of COVID-19 and other viral factors using RNA interference is considered.

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Publication Details

Journal
Russian Journal of Genetics
Published
2025-12-01
DOI
https://doi.org/10.1134/s1022795425701133
Primary Topic
Immune responses and vaccinations
Type
article
Field-Weighted Citation Impact
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article

Epigenetic Approaches to Diagnosis and Therapy of COVID-19: Features of Differential DNA Methylation Profile as Potential Targets for Therapy by the Method of RNA Interference

S. A. Borinskaya, O. B. Belopolskaya, N. K. Yankovsky, A. A. Rimskaya et al.
Russian Journal of Genetics
Immune responses and vaccinations
article

Epigenetic Approaches to Diagnosis and Therapy of COVID-19: Features of Differential DNA Methylation Profile as Potential Targets for Therapy by the Method of RNA Interference

S. A. Borinskaya, O. B. Belopolskaya, N. K. Yankovsky, A. A. Rimskaya, N. V. Markina
article en

Abstract

In this article the role of epigenetic factors, in particular, DNA methylation, in the processes of interaction of the SARS-CoV-2 virus with the human body and in the pathogenesis of COVID-19 is considered. An overview of experimental studies on the use of microRNA to regulate the expression of genes processed during the interaction of the virus with the host body is presented. A potential new strategy in the diagnosis and therapy of COVID-19 and other viral factors using RNA interference is considered.

Russian Journal of GeneticsVol. 61(12)
Vavilov Institute of General Genetics (RU)
Good health and well-being
Openalex Percentile: Top 36%
Immune responses and vaccinations
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