Impact of statin therapy on postoperative outcomes following colorectal cancer surgery: A systematic review

Statin therapy may confer short-term survival benefits in CRC surgical patients, potentially <i>via</i> anti-inflammatory or cytoprotective mechanisms. While evidence regarding anastomotic leaks remains inconclusive, trends suggest improved postoperative outcomes. These findings are constrained by methodological heterogeneity, underscoring the need for prospective, randomized studies to confirm benefits and identify optimal patient subgroups.