Flortaucipir patterns in preclinical Alzheimer's disease: an evaluation of TRAILBLAZER‐ALZ 3 baseline data

Although CDR0.5 subgroup participants demonstrated higher mean FTP regional SUVR values compared with CDR0 participants, the baseline tau PET patterns in TRAILBLAZER-ALZ 3 are similar to other preclinical AD populations, even for participants in the CDR0.5 subgroup. Average regional baseline SUVR values support prior findings that tau deposition occurs sequentially from the medial temporal, lateral temporal, parietal, and frontal lobes. Additional regional analyses will be presented.