Cortical‐subcortical functional connectivity alterations are associated with mild behavioral impairment in Asian dementia‐free older adults
Our findings demonstrated the association between cortical-subcortical functional alterations in DMN and MBI. Furthermore, cerebrovascular pathology and neuroinflammation processes may play an important role in modulating this brain-behavior relationship, which warrants for further investigation.
Authors
- Cheuk Ni Kan (ORCID: https://orcid.org/0000-0001-8574-1243)
- Shi Yu Chan (ORCID: https://orcid.org/0000-0002-6261-0440)
- Yingqi Liao (ORCID: https://orcid.org/0000-0001-7499-8801)
- Joyce Ruifen Chong (ORCID: https://orcid.org/0000-0002-2869-0096)
- Christopher Chen
- Ai Peng Tan
Institutions
- Agency for Science, Technology and Research (SG)
- National University of Singapore (SG)
- Singapore Institute for Clinical Sciences (SG)
- National University Health System (SG)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101460
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00