Cognitive decline according to Amyloid Uptake in patients with postStrokE cognitive impairment

The presence of amyloid plaques in PSCI patients is associated with a faster cognitive decline, as evidenced by the lower MMSE and worsening CDR-SOB scores in the amyloid-positive group. Although donepezil shows short-term cognitive benefits, its impact diminishes over time. Early identification of amyloid deposition could be crucial in guiding personalized therapeutic strategies for managing PSCI effectively.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_101232
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cognitive decline according to Amyloid Uptake in patients with postStrokE cognitive impairment

B D Ku, Jae‐Won Jang, YongSoo Shim, Seunghee Na et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Cognitive decline according to Amyloid Uptake in patients with postStrokE cognitive impairment

B D Ku, Jae‐Won Jang, YongSoo Shim, Seunghee Na, Yun Jeong Hong
article en

Abstract

The presence of amyloid plaques in PSCI patients is associated with a faster cognitive decline, as evidenced by the lower MMSE and worsening CDR-SOB scores in the amyloid-positive group. Although donepezil shows short-term cognitive benefits, its impact diminishes over time. Early identification of amyloid deposition could be crucial in guiding personalized therapeutic strategies for managing PSCI effectively.

Alzheimer s & DementiaVol. 21(S3)
Kangwon National University (KR), The Catholic University of Korea Incheon St. Mary's Hospital (KR), The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR), Catholic Kwandong University International St. Mary's Hospital (KR), Catholic University of Korea (KR)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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