Developing a Novel Genomic Biomarker for the Early Detection of Neurodegeneration
While preliminary results for detection of neuron-derived cfDNA as a biomarker neurodegeneration are promising, further development of cell type deconvolution methods and testing of diagnostic capability in patient populations are required in order to draw conclusions about the clinical utility of this assay.
Authors
- Eilis J. Hannon (ORCID: https://orcid.org/0000-0001-6840-072X)
- Timothy Harrower (ORCID: https://orcid.org/0000-0002-2558-9726)
- Emma Louise Dempster (ORCID: https://orcid.org/0000-0003-1257-5314)
- Barry A. Chioza (ORCID: https://orcid.org/0000-0002-3546-1726)
- Rosemary A. Bamford
- Jonathan Mill
- Martyn Frith
Institutions
- University of Exeter (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099024
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00