Sodium channel subtype Na <sub>v</sub> 1.3 is associated with increased hippocampal CA3 neuronal activity in early Alzheimer's Disease

Our findings identify a novel Na<sub>v</sub> subtype (Na<sub>v</sub>1.3) re-expressed in early stages of AD coinciding with sex dependent hippocampal CA3 hyperexcitability.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_098112
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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Sodium channel subtype Na v 1.3 is associated with increased hippocampal CA3 neuronal activity in early Alzheimer's Disease

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Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Sodium channel subtype Na v 1.3 is associated with increased hippocampal CA3 neuronal activity in early Alzheimer's Disease

Kishan Patel, Jimcy Platholi, Jiabin Tang, Jiaxin Xiang, Hugh C Hemmings
article en

Abstract

Our findings identify a novel Na<sub>v</sub> subtype (Na<sub>v</sub>1.3) re-expressed in early stages of AD coinciding with sex dependent hippocampal CA3 hyperexcitability.

Alzheimer s & DementiaVol. 21(S2)
Cornell University (US), Weill Cornell Medicine (US)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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