Analysis of reasons for screen failure by participant race in the Phase 2 Auτonomy study in early Alzheimer's disease

This analysis showed numerically higher overall SF rates amongst Black/African American population compared with other races evaluated. The Black/African American population had a higher proportion of SF due to the early AD clinical inclusion criterion compared with the White population; however, comparison is limited by the low number of Black/African American participants screened. Analysis of SF data from existing AD trials may help inform on recruiting a diverse study population by furthering understanding of any racial differences in underlying AD pathophysiology levels or co-morbidities contributing to cognitive impairment.