Connexin‐50 role in spreading of polymorphic alpha‐synuclein in Synucleiopathy
This study presents compelling evidence of the connection between disease-relevant α-Syn aggregates and Cx50 in neurons that regulate astrocyte activity. This insight sheds light on the intricate process of pathogenic α-Syn spread in Synucleiopathies.
Authors
- Rakez Kayed
- Nemil Bhatt (ORCID: https://orcid.org/0000-0001-5017-7312)
- Abbigael E Aday
- Cynthia Jerez (ORCID: https://orcid.org/0009-0002-2678-1127)
- Nikita Shchankin
- Nicha Puangmalai (ORCID: https://orcid.org/0000-0002-1138-237X)
- Urmi Sengupta (ORCID: https://orcid.org/0000-0002-8034-6241)
- Mauro Montalbano (ORCID: https://orcid.org/0000-0002-2054-625X)
- Jai Yi Liew
- Fadhl Al‐Shaebi
Institutions
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105939
- Primary Topic
- Connexins and lens biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00