A resource of data and samples in cognitively unimpaired 60–75‐year‐olds at increased risk of Alzheimer's disease based on their <i>APOE4</i> status as heterozygotes or homozygotes
The API Generation Program data and biological samples offer researchers a chance to further assess some of the earliest biological and cognitive changes associated with the predisposition to the disease, evaluate initial effects of the two investigational anti-amyloid treatments, and help inform the design of future prevention trials. Data and samples are available for sharing and can be requested through the Imaging and Data archive at https://ida.loni.usc.edu, the Alzheimer's Disease workbench at https://Alzheimersdata.org/ad-workbench, or by email at [email protected].
Authors
- Pierre N. Tariot (ORCID: https://orcid.org/0000-0002-6058-8032)
- Carolyn Langlois
- Hayley Salata
- Vivek Devadas
- Jeremy J. Pruzin (ORCID: https://orcid.org/0000-0002-0443-4194)
- Jessica Enos
- Jessica B. Langbaum (ORCID: https://orcid.org/0000-0003-3848-1324)
- Christopher Brown (ORCID: https://orcid.org/0000-0002-5798-6769)
- Trisha Walsh
- Yi Su
- Eric M. Reiman
Institutions
- University of Arizona (US)
- Mayo Clinic in Arizona (US)
- Banner Alzheimer’s Institute
- Arizona State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107073
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00