Sex‐specific effects of neuropsychiatric symptoms on amyloid and tau pathology and white matter hyperintensity volume in preclinical Alzheimer's disease
We found associations between NPS and both MRI and PET markers of AD in cognitively unimpaired individuals at risk of AD. Some of these associations were stronger in males, despite females being at increased risk of AD and known to exhibit a higher prevalence of NPS.
Authors
- Mahsa Dadar (ORCID: https://orcid.org/0000-0003-4008-2672)
- Valentin Ourry (ORCID: https://orcid.org/0000-0002-8535-9009)
- Alfonso Fajardo
- Yara Yakoub (ORCID: https://orcid.org/0000-0002-4769-7162)
- Sylvia Villeneuve (ORCID: https://orcid.org/0000-0003-2338-0467)
- Aurelie Garrone
- Amelie Metz (ORCID: https://orcid.org/0000-0001-9104-5383)
- Ting Qiu
Institutions
- Douglas Mental Health University Institute (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_103725
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00