AI‐driven Amyloid Pathology Detection Using Multi‐modal MRI: A Proof of Concept Study

This proof of concept work provides a preliminary method to make amyloid detection safer, more affordable, and more accessible for patients and the healthcare industry. The technology leverages routinely acquired MRI scans to extract additional clinical insights, offering a non-invasive tool for identifying candidates eligible for early disease-modifying therapies. While further improvements to the model accuracy are ongoing, this approach has the potential to improve early detection and patient prognosis.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_099593
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

AI‐driven Amyloid Pathology Detection Using Multi‐modal MRI: A Proof of Concept Study

Manmohi Dake, Ashwin Venkataraman, Dag Aarsland, Himank Kavathekar
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

AI‐driven Amyloid Pathology Detection Using Multi‐modal MRI: A Proof of Concept Study

Manmohi Dake, Ashwin Venkataraman, Dag Aarsland, Himank Kavathekar
article en

Abstract

This proof of concept work provides a preliminary method to make amyloid detection safer, more affordable, and more accessible for patients and the healthcare industry. The technology leverages routinely acquired MRI scans to extract additional clinical insights, offering a non-invasive tool for identifying candidates eligible for early disease-modifying therapies. While further improvements to the model accuracy are ongoing, this approach has the potential to improve early detection and patient prognosis.

Alzheimer s & DementiaVol. 21(S2)
Government of Maharashtra (IN), Wellcome Centre for Human Neuroimaging (GB), King's College London (GB), South London and Maudsley NHS Foundation Trust (GB), Stavanger University Hospital (NO)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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