Beyond Arg39: new insights into antiphospholipid antibodies
revealed a novel female-specific association at the CDH22/CD40 locus, where the risk allele increases susceptibility to PV but protects from ET.The authors propose that this PV-specific risk variant may interact with sex-specific biological processes, although mechanisms at this locus remain to be clarified.
Authors
- Rolf T. Urbanus (ORCID: https://orcid.org/0000-0002-1601-9393)
Institutions
- Utrecht University (NL)
Publication Details
- Journal
- Blood
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1182/blood.2025031543
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00