A Glowing Clot”: FDG PET/CT Identifies Persistent Tumour Thrombus in Metastatic Lung Carcinoma

Tumour thrombi are a rare but serious complication of malignancy. It involves extension of organised collection of neoplastic cells into adjacent blood vessels, in contrast to a bland thrombus which consists of platelets and fibrin. It occurs more commonly in renal cell or hepatic cell carcinoma. Tumour thrombi are often asymptomatic and incidentally detected on imaging, however, their presence can affect staging, treatment options and prognosis of the patient. We present a rare case of a FDG avid tumour thrombus in left brachiocephalic vein in a patient with previously treated metastatic urothelial carcinoma and a second primary lung carcinoma.

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Publication Details

Journal
Journal of the Pakistan Medical Association
Published
2025-12-20
DOI
https://doi.org/10.47391/jpma.26-07
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00
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article

A Glowing Clot”: FDG PET/CT Identifies Persistent Tumour Thrombus in Metastatic Lung Carcinoma

Aimen Anis, Sana Munir Gill, Mairah Razi
Journal of the Pakistan Medical Association
Cardiac tumors and thrombi
article

A Glowing Clot”: FDG PET/CT Identifies Persistent Tumour Thrombus in Metastatic Lung Carcinoma

Aimen Anis, Sana Munir Gill, Mairah Razi
article en

Abstract

Tumour thrombi are a rare but serious complication of malignancy. It involves extension of organised collection of neoplastic cells into adjacent blood vessels, in contrast to a bland thrombus which consists of platelets and fibrin. It occurs more commonly in renal cell or hepatic cell carcinoma. Tumour thrombi are often asymptomatic and incidentally detected on imaging, however, their presence can affect staging, treatment options and prognosis of the patient. We present a rare case of a FDG avid tumour thrombus in left brachiocephalic vein in a patient with previously treated metastatic urothelial carcinoma and a second primary lung carcinoma.

Journal of the Pakistan Medical AssociationVol. 76(01)
Shaukat Khanum Memorial Cancer Hospital and Research Center (PK)
Good health and well-being
Openalex Percentile: Top 31%
Cardiac tumors and thrombi
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