Study Design of Draw‐10: a weekly blood draw study to understand the biological fluctuations of plasma pTau‐217

The Draw-10 study addresses the need for further understanding the biological variation of AD blood biomarkers and for identifying potential sources of fluctuations in their levels. These results may improve biomarker-supported clinical decisions, prevent inappropriate blood biomarker based screening decisions of research participants and determining the minimum number of samples required for a reliable p-Tau217 measurement.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_100492
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Study Design of Draw‐10: a weekly blood draw study to understand the biological fluctuations of plasma pTau‐217

Wagner S. Brum, Nicholas Ashton, Carolyn Langlois, Nellie High et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Study Design of Draw‐10: a weekly blood draw study to understand the biological fluctuations of plasma pTau‐217

Wagner S. Brum, Nicholas Ashton, Carolyn Langlois, Nellie High, Jessica B. Langbaum, Kaj Blennow, Marisa N. Denkinger, Trisha Walsh, Kari Dieckhoff, James Liu, Claire M Erickson, Ricquee Gonzalez‐Green, Eric M. Reiman
article en

Abstract

The Draw-10 study addresses the need for further understanding the biological variation of AD blood biomarkers and for identifying potential sources of fluctuations in their levels. These results may improve biomarker-supported clinical decisions, prevent inappropriate blood biomarker based screening decisions of research participants and determining the minimum number of samples required for a reliable p-Tau217 measurement.

Alzheimer s & DementiaVol. 21(S2)
Banner Sun Health Research Institute (US), Banner Alzheimer’s Institute, University of Gothenburg (SE)
Quality Education
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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Study Design of Draw‐10: a weekly blood draw study to understand the biological fluctuations of plasma pTau‐217 — Wagner S. Brum, Nicholas Ashton, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS