Amyloid β‐induced cardiac neurotrophic signaling disruption drives heart dysfunction in Alzheimer's disease

Collectively, our research unveils a previously unrecognized mechanism by which Aβ dysregulates cardiac neurotrophic signaling, emphasizing the relevance of cardiac degeneration in AD. Our findings highlight the importance of addressing cardiac complications in AD management, thus opening novel translational avenues for future precision medicine investigations that may help to reevaluate the clinical approaches to AD therapy.