Posterior cortical atrophy: Reorganization of the dorsal attention network and its implications on volume loss and clinical performance

These findings suggest that within- and between-network connectivity of the dorsal attention network, both within key regions and the entire network, was disrupted in PCA patients. However, this network did not show disrupted connectivity with the core PCA networks. Within-network connectivity disruptions in the dorsal attention network are associated with aspects of memory function, and to some extent, with volume loss.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_099776
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Posterior cortical atrophy: Reorganization of the dorsal attention network and its implications on volume loss and clinical performance

Val J. Lowe, R. C. Petersen, Jonathan Graff‐Radford, D S Knopman et al.
Alzheimer s & Dementia
Functional Brain Connectivity Studies
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Posterior cortical atrophy: Reorganization of the dorsal attention network and its implications on volume loss and clinical performance

Val J. Lowe, R. C. Petersen, Jonathan Graff‐Radford, D S Knopman, Mary M. Machulda, Jennifer L. Whitwell, Christopher G Schwarz, Neha Singh‐Reilly, Clifford R. Jack, Keith A. Josephs
article en

Abstract

These findings suggest that within- and between-network connectivity of the dorsal attention network, both within key regions and the entire network, was disrupted in PCA patients. However, this network did not show disrupted connectivity with the core PCA networks. Within-network connectivity disruptions in the dorsal attention network are associated with aspects of memory function, and to some extent, with volume loss.

Alzheimer s & DementiaVol. 21(S2)
Mayo Clinic (US), WinnMed (US), Mayo Clinic in Arizona (US)
Openalex Percentile: Top 33%
Functional Brain Connectivity Studies
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