Associations Between Brain Microstructure, Cognition and Socioeconomic Factors in a Diverse Cohort : the LASI‐DAD Study
These findings support the role of neurite density, as measured by FICVF, in predicting cognitive outcomes in community-based populations. Interestingly, a stronger FICVF-cognition relationship was observed among individuals with disadvantaged socioeconomic backgrounds. Specifically, lower risks of MCI associated with increased FICVF were seen in those who are illiterate, literate with reading errors, have lower education, are unemployed, or reside in urban areas, compared to their counterparts.
Authors
- Leon Aksman (ORCID: https://orcid.org/0000-0003-2342-0780)
- Pranali Khobragade (ORCID: https://orcid.org/0000-0002-1117-1177)
- Yingxu Liu (ORCID: https://orcid.org/0000-0002-5053-4911)
- Kirsten M. Lynch (ORCID: https://orcid.org/0000-0003-3976-5783)
- Niranjan Khandelwal
- Joyita Banerjee
- Jinkook Lee
Institutions
- University of Southern California (US)
- NIMS University (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099412
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00