Association of wisdom and AD pathologic burden in cognitively unimpaired older adults
Wisdom, a traditional, higher-order construct of mental functioning, was not related to education, IQ, or subjective or objective cognition in this sample of CU older adults. Wisdom encompasses qualities of decisiveness, self-reflection and social intelligence that may be sensitive to Aβ pathologic burden and could be a measurable, unrecognized sign of preclinical AD.
Authors
- David H. Adamowicz (ORCID: https://orcid.org/0000-0002-4769-9096)
- Nancy J. Donovan (ORCID: https://orcid.org/0000-0002-6328-1589)
- Benjamin S. Zide (ORCID: https://orcid.org/0009-0003-5621-8850)
- K. N. Johnson
- S. Lee (ORCID: https://orcid.org/0000-0002-9223-8512)
- Jessa Burling
- Dorene M. Rentz
- Reisa A. Sperling
Institutions
- Broad Institute (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_099065
- Primary Topic
- Aging and Gerontology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00