Traumatic brain injury derived pathological tau polymorphs induce the distinct propagation pattern and neuroinflammatory response

Collectively, our results shed light on the intricate mechanisms underlying TBI-BDTP-induced tau pathology and its association with neuroinflammatory processes. This investigation enhances our understanding of tauopathies and their interplay with neurodegenerative and inflammatory pathways following traumatic brain injury.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_105934
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Traumatic brain injury derived pathological tau polymorphs induce the distinct propagation pattern and neuroinflammatory response

Rakez Kayed, Nemil Bhatt, Cynthia Jerez, Nikita Shchankin et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Traumatic brain injury derived pathological tau polymorphs induce the distinct propagation pattern and neuroinflammatory response

Rakez Kayed, Nemil Bhatt, Cynthia Jerez, Nikita Shchankin, Nicha Puangmalai, Madison Samples
article en

Abstract

Collectively, our results shed light on the intricate mechanisms underlying TBI-BDTP-induced tau pathology and its association with neuroinflammatory processes. This investigation enhances our understanding of tauopathies and their interplay with neurodegenerative and inflammatory pathways following traumatic brain injury.

Alzheimer s & DementiaVol. 21(S1)
The University of Texas Medical Branch at Galveston (US)
Good health and well-being
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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