Genome‐wide association study for Alzheimer's disease related complement components and regulators
Our study identified significant associations between plasma levels of complement proteins and domain-specific cognitive scores, highlighting their potential relevance to Alzheimer's disease (AD) pathology. These findings provide valuable insights into the genetic regulation of complement pathways in AD and suggest potential mechanisms underlying their role in cognitive decline.
Authors
- Gyungah R Jun
- Samantha Clayton
Institutions
- Boston University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107268
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00