Neuronal reprogramming improves brain health in TgAD and aging rats
Neuronal reprogramming decreases neuroinflammation and increases survival of neurons within the hippocampus of both TgF344 AD and aging F344 non-transgenic littermates. We demonstrate the return to a more homeostatic brain environment post-neuronal reprogramming in middle-aged and older rats.
Authors
- JoAnne McLaurin
- Tina L. Beckett
- Mary Hill
- Jessica A. Ribeiro
Institutions
- University of Toronto (CA)
- Sunnybrook Hospital (CA)
- Sunnybrook Research Institute
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107476
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00