Neuronal Cell‐Type Susceptibility in CA1 in 5xFAD Mice

In the CA1, discrete neurons are primarily susceptible to AD neurodegeneration in the 5xFAD mouse model. Future studies will investigate the transcriptomic changes that occur within vulnerable CA1 neurons that precede death.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_105879
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Neuronal Cell‐Type Susceptibility in CA1 in 5xFAD Mice

A Huete Hurtado, Maricarmen Pachicano, Michael Bienkowski, Shrey Mehta
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Neuronal Cell‐Type Susceptibility in CA1 in 5xFAD Mice

A Huete Hurtado, Maricarmen Pachicano, Michael Bienkowski, Shrey Mehta
article en

Abstract

In the CA1, discrete neurons are primarily susceptible to AD neurodegeneration in the 5xFAD mouse model. Future studies will investigate the transcriptomic changes that occur within vulnerable CA1 neurons that precede death.

Alzheimer s & DementiaVol. 21(S1)
University of Southern California (US)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
DOIOpen Access PDFOpenAlex
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Neuronal Cell‐Type Susceptibility in CA1 in 5xFAD Mice — A Huete Hurtado, Maricarmen Pachicano, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS