Sex‐specific immune cell signatures define clinical stages and severity of Alzheimer's disease
The immune cell changes identified here were distinct among cellular phenotypes in peripheral blood and CSF in their responsiveness to AD pathological changes and show promise for novel biomarkers and future immune related therapeutics in AD.
Authors
- Penelope Benchek (ORCID: https://orcid.org/0000-0002-7385-087X)
- M. J. Lowe
- Aaron Burberry (ORCID: https://orcid.org/0000-0003-1552-8695)
- Sara Ramaiah
- Blake McCourt (ORCID: https://orcid.org/0000-0002-1488-2572)
- William S. Bush (ORCID: https://orcid.org/0000-0002-9729-6519)
- Holden T. Maecker (ORCID: https://orcid.org/0000-0003-0795-9946)
- Lynn M. Bekris (ORCID: https://orcid.org/0000-0002-2747-7672)
- Maria Khrestian (ORCID: https://orcid.org/0000-0002-1621-4711)
- Stephen M. Rao
- Jagan A Pillai
- Quintasha Beamon
- Elizabeth Woidke
- Wanyong Shin
- James B Leverenz
Institutions
- Cleveland Clinic (US)
- Lou Ruvo Brain Institute (US)
- Case Western Reserve University (US)
- Stanford University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103630
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00